An illustrator for the Saturday Evening Post, Henry Soulen began that career in May, 1912, having been a student of Howard Pyle. He also worked for other publications including Country Gentleman and Ladies Home Journal and earned a Peabody Award for his magazine cover designs.

He was known for his use of intense, brilliant color and at a time when many illustrations were in black and white, his usually appeared in color. 

He was a thorough researcher and eventually collected a large and varied collection of costumes, weapons, and other objects that he used in his drawings. 

At age 62, he became a college professor at the University of Maryland and taught the first illustration that art department offered.

During World War II, he gave free art lessons at the Valley Forge Military Hospital, a rehabilitation center for veterans.